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Deregulation of normal transcription is a feature of all types of acute leukaemia. In T-ALL, this is brought about by altered expression of normal transcription factor proteins.
T-ALL is a feature of between 12 to 15% of childhood ALL. In about 30% of these cases, chromosomal translocations involving the T-cell receptor genes TRA@ (TCRA), TRB@ (TCRB), TRG@ (TCRG) and TRD@ (TCRD) have been described.
Cat. No. LPH 047-S (5 tests)
Cat. No. LPH 047 (10 tests)
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